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About Blog Download Explore Help YeastMine Get Data Email Us Facebook Linkedin YouTube Saccharomyces Genome Database Saccharomyces Genome Database Saccharomyces Genome Database Menu Analyze Gene Lists BLAST Fungal BLAST GO Term Finder GO Slim Mapper Pattern Matching Design Primers Restriction Site Mapper Sequence Download Genome Browser BLAST Fungal BLAST Gene/Sequence Resources Reference Genome Download Genome Genome Snapshot Chromosome History Systematic Sequencing Table Original Sequence Papers Strains and Species Variant Viewer Align Strain Sequences Resources UniProtKB InterPro (EBI) HomoloGene (NCBI) YGOB (Trinity College) AlphaFold Function Gene Ontology GO Term Finder GO Slim Mapper GO Slim Mapping File Expression Biochemical Pathways Phenotypes Browse All Phenotypes Interactions YeastGFP Resources GO Consortium BioGRID (U. Toronto) Literature Full-text Search New Yeast Papers YeastBook Genome-wide Analysis Papers Resources PubMed (NCBI) PubMed Central (NCBI) Google Scholar Community Community Forum Colleague Information Find a Colleague Add or Update Info Find a Yeast Lab Career Resources Education Meetings Nomenclature Submit a Gene Registration Gene Registry Nomenclature Conventions Methods and Reagents Strains and Constructs Reagents Protocols and Methods Historical Data Physical & Genetic Maps Genetic Maps Genetic Loci ORFMap Chromosomes Sequence Gene Summary Paragraphs Wiki Submit Data Resources API Info & Downloads About Blog Downloads Site Map Help Hsf1p-target genes (green) coalesce into foci after heat shock (nuclear pore complex, red). Image courtesy of S. Chowdhary and A. Kainth, Gross Lab, LSU Health Sciences Center. Rap1-GFP and Calcofluor White staining of stationary phase cells. Image courtesy of M. Guidi, M. Ruault and A. Taddei, Institut Curie (Paris). Pma1-mCherry and Vma1-GFP localization in mitotic cells. Image courtesy of M. Eastwood, Fred Hutch and M. Meneghini, University of Toronto. CCCP-induced decrease of mitochondrial membrane potential (below) or control treatment (above) as measured by MitoLoc. Image courtesy of Dr. Jakob Vowinckel, Ralser Lab, University of Cambridge. Redistribution of Msn5 pools from the nucleus to the cytoplasm upon glucose deprivation. Image courtesy of H. Huang and A. Hopper, Ohio State University. Floccule of yeast rho0 cells expressing PTS1-GFP as a peroxisomal marker, stained with calcofluor white. Image courtesy of Dr. Jakob Vowinckel, University of Cambridge S. cerevisiae membrane proteins visualized by RFP and GFP. Image courtesy of Masur. Wikimedia Commons. Peroxisome (red) and mitochondrial (green) fission defects in vps1 fis1 double deletion strain transformed with FIS1. Image courtesy of S. Lefevre, S. Kumar and I. van der Klei, University of Groningen. Yeast cells expressing TRK1/GFP. Image courtesy of V. Zayats and J. Ludwig, Center of Nanobiology and Structural Biology, AV CR. The distribution of mtDNA (green) within the mitochondrial network (red). Image courtesy of Christof Osman and Peter Walter, University of California, San Francisco The distribution of ER exit sites (ERES, green) within the ER (red). Image courtesy of A. Nakano and K. Kurokawa, RIKEN. Cell, actin and nuclear morphology of yeast cells treated with DMSO (left) and poacic acid (right). Images courtesy of Hiroki Okada and Yoshikazu Ohya, University of Tokyo. Localization of active Ras in a wild type strain Image courtesy of S. Colombo and E. Martegani, University Milano Bicocca Sectored colonies showing loss of silencing at the HML locus Image courtesy of Anne Dodson, UC Berkeley Pma1p imaged using the RITE tagging system in mother (green) and daughter cells (red) Image courtesy of Dan Gottschling Ph.D., Fred Hutchinson Cancer Research Center Lipid droplets in fld1 mutant images by CARS Image courtesy of Heimo Wolinski, Ph.D. and Sepp D. Kohlwein, Ph.D., University of Graz, Austria Fpr3p accumulation in the nucleolus of S. cerevisiae Image courtesy of Amy MacQueen, Ph.D., Wesleyan University anti-Fpr3 antibody courtesy of Jeremy Thorner, Ph.D., UC Berkeley San1 strain visualized with FUN and calcofluor white Image courtesy of the Bruschi lab, ICGEB, Trieste, Italy Single MDN1 mRNAs detected by FISH Image courtesy of the Zenklusen Lab, Université de Montréal Localization of Ace2-GFP to daughter cell nuclei Image courtesy of Eric Weiss, Ph.D. Northwestern University About SGD The Saccharomyces Genome Database (SGD) provides comprehensive integrated biological information for the budding yeast Saccharomyces cerevisiae along with search and analysis tools to explore these data, enabling the discovery of functional relationships between sequence and gene products in fungi and higher organisms. Explore SGD Meetings 16th Yeast Lipid Conference May 29 to May 31, 2024 - Saarland University, Homburg, Germany RCN-UBE: Yeast ORFan Gene Project - Summer Workshop - Gene Expression Analysis June 20 to June 21, 2024 - Virtual FASEB Yeast Chromosome Biology and Cell Cycle June 23 to June 27, 2024 - Fort Garry Hotel, Winnipeg, Manitoba, Canada JCS2024: Diversity and Evolution in Cell Biology June 24 to June 27, 2024 - Montanya Hotel & Lodge, Catalonia, Spain 39th Small Meeting of Yeast Transporters and Energetics (SMYTE) August 28 to September 01, 2024 - University of York, York, United Kingdom ICY2024: 16th International Congress on Yeasts September 29 to October 03, 2024 - Cape Town International Convention Centre, Cape Town, South Africa Yeast2025: 32nd International Conference on Yeast Genetics and Molecular Biology ICYGMB32 July 21 to July 24, 2025 - Sorbonne University, Paris, France New & Noteworthy Deadline extended to April 22 for the 2024 Yeast Genetics and Genomics Course - April 09, 2024 The application deadline for the 2024 Yeast Genetics and Genomics Course has been extended to April 22 – don’t miss your chance! Significant financial aid may be available for trainees applying, covering up to 50% of the cost of the course! Find all the details and application form at the CSHL Meetings & Courses site. […] Read More New user interface for YeastMine - April 04, 2024 Here at SGD we provide high-quality curated genomic, genetic, and molecular information on the genes and gene products of the budding yeast Saccharomyces cerevisiae. Twelve years ago, in order to accommodate the increasingly complex and diverse needs of researchers for searching and comparing data, SGD implemented InterMine, an open source data warehouse system with a […] Read More Changes to Saccharomyces cerevisiae GFF3 file - March 01, 2024 The saccharomyces_cerevisiae.gff contains sequence features of Saccharomyces cerevisiae and related information such as Locus descriptions and GO annotations. It is fully compatible with Generic Feature Format Version 3. It is updated weekly. After November 2020, SGD updated the transcripts in the GFF file to reflect the experimentally determined transcripts (Pelechano et al. 2013, Ng et […] Read More Apply Now for the 2024 Yeast Genetics and Genomics Course - February 13, 2024 For over 50 years, the legendary Yeast Genetics & Genomics course has been taught each summer at Cold Spring Harbor Laboratory, though the name didn’t include Genomics” in the beginning. The list of people who have taken the course reads like a Who’s Who of yeast research, including Nobel laureates and many of today’s leading […] Read More SGD Newsletter, December 2023 - December 13, 2023 About this newsletter:This is the December 2023 issue of the SGD newsletter. The goal of this newsletter is to inform our users about new features in SGD and to foster communication within the yeast community. You can view this newsletter, as well as previous newsletters, on the SGD...